Highway 35
From Santa Cruz County history wiki
State Highway 35 (officially "California State Route 35") begins at its junction with Highway 17, near the line dividing Santa Cruz and Santa Clara counties. From there it runs northwest along that county line to exit the county at its northern tip and continue to its eventual terminus in San Francisco. In Santa Cruz County, the local name for the highway is Skyline Boulevard.
Only one state highway originates elsewhere on both ends and passes through Santa Cruz County: Highway 1. Five highways originate in Santa Cruz County and pass out of it: Highway 9, Highway 17, Highway 35, Highway 129, Highway 152. One begins and ends within the county: Highway 236.